Avantor, Inc.

Operating cash flow of $207 million free cash flow of $172 million Company announces $500 million share repurchase authorization, reflecting confidence in cash generation and commitment to driving long-term shareholder value RADNOR, Pa.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

I strongly believe in Avantor s growth and profitability potential, and this conviction is reflected in the new $500 million share repurchase program our Board has authorized.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

Adjusted Operating Income is our net income or loss adjusted for the following items (i) interest expense, (ii) income tax expense, (iii) amortization of acquired intangible assets, (iv) losses on extinguishment of debt, (v) charges associated with the impairment of certain assets, (vi) gain on sale of business, and (vii) certain other adjustments.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

Adjusted EBITDA is our net income or loss adjusted for the following items (i) interest expense, (ii) income tax expense, (iii) amortization of acquired intangible assets, (iv) depreciation expense, (v) losses on extinguishment of debt, (vi) charges associated with the impairment of certain assets, (vii) gain on sale of business, and (viii) certain other adjustments.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

Adjusted net income is our net income or loss first adjusted for the following items (i) amortization of acquired intangible assets, (ii) losses on extinguishment of debt, (iii) charges associated with the impairment of certain assets, (iv) gain on sale of business, and (v) certain other adjustments.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

Adjusted net leverage is equal to our gross debt, reduced by our cash and cash equivalents, divided by our trailing 12-month Adjusted EBITDA (excluding stock-based compensation expense and including the expected run-rate effect of cost synergies and the incremental results of completed acquisitions and divestitures as if those acquisitions and divestitures had occurred on the first day of the trailing 12-month period).

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

We are taking action to evolve our go-to-market approach, sharpen our customer value proposition, and invest strategically in our manufacturing and supply chain.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

We believe that this measure is useful to investors as a way to evaluate and measure the Company s capital allocation strategies and the underlying trends in the business.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

Forward-looking statements discuss our current expectations and projections relating to our financial condition, results of operations, plans, including our cost transformation initiative, objectives, future performance and business.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

Reflects the incremental expenses incurred in the period related to restructuring initiatives to increase profitability and productivity.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

These expenses represent costs incurred to achieve the Company s publicly-announced cost transformation initiative.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

Forward-looking statements are inherently subject to risks, uncertainties and assumptions they are not guarantees of performance.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

Factors that could contribute to these risks, uncertainties and assumptions include, but are not limited to, the factors described in Risk Factors in our most recent Annual Report on Form 10-K, and subsequent quarterly reports on Form 10-Q, as such risk factors may be updated from time to time in our periodic filings with the SEC.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025

Represents charges and legal costs, net of recoveries, in connection with certain litigation and other contingencies that are unrelated to our core operations and not reflective of on-going business and operating results.

SEC original ↗Avantor, Inc. — Earnings release (8-K exhibit)EX-99Oct 29, 2025